In our latest episode of Clinical Grade, you’ll meet two remarkable individuals playing important roles in the fight against chronic kidney disease (CKD). First, we speak with Dr. Josef Coresh, Professor of Epidemiology, Biostatistics & Medicine at Johns Hopkins University. Not only is Dr. Coresh one of the world’s leading kidney disease experts—he helped classify the disease, and shaped the clinical guidelines for treating it. We discuss the high prevalence and low public profile of chronic kidney disease, the mechanics of early detection, and some reasons for optimism.